Differentiation of Azacitidine vs Oral AZA: Oral AZA results in a sustained hypomethylation and targets leukemic stem cells.

Congratulations to Nathalie Lailler and Chris Hartl for being named on an abstract that has been accepted for poster presentation at the American Society for Hematology meeting in December.

Rancho BioSciences

Rancho BioSciences wins Leading Expertis in Data Curation & Analytics 2021 - California.

Rancho BioSciences

NCATS Inxight Drugs: a comprehensive and curated portal for translational research.

Congratulations to Ivan Grishagin, Yulia Skovepen, Oleg Stroganov, and Daniel Katzel for their contribution.

Rancho BioSciences

Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials.

Alexander Arefolov, Laura Adam, Shoshana Brown, Yelena Budovskaya, Cong Chen, Diya Das, Chen Farhy, Rebecca Ferguson, Hongmei Huang, Kimberly Kanigel, Christina Lu, Oksana Polesskaya, Tracy Staton, Rajeev Tajhya, Maryann Whitley, Jee-Yeon Wong, Xiangpei Zeng & Mark McCreary, Data Intelligence 2021,3(4):631–662.

Rancho BioSciences

The CHDI/Rancho publication is available as preprint

Rancho BioSciences

Assessing safety of telemetric devices in preclinical studies of primates – data aggregation step.

Rancho BioSciences

Rancho provides funds for a pilot project to fast-track the development of affordable cancer treatments.

Rancho BioSciences

Towards a comprehensive view of diagnoses in UK Biobank by data curation and aggregation.

Rancho BioSciences

Application of MCAT questions as a testing tool and evaluation metric for knowledge graph–based reasoning systems.

Rancho BioSciences

HD Phenocopy Disease Share Dysregulated Genes with HD.

Rancho BioSciences

HD Mouse Striatum RNA and Protein Disease Signatures

On June 23rd 2021 we held a joint webinar with GSK on a large scale project around harmonizing OMICs datasets in Oncology/Immuno-Oncology.

The abstract is below, slides and recording can be downloaded below.

These pre-competitive data sets are available now on a cost sharing basis.


CDK is an open source Cheminformatics Java Library that has been under development for over 20 years. Recently, CDK released version 2.5, which includes several bug fixes. The CDK library is widely used in the FDA G-SRS project, and it assists agencies in registering and documenting information about substances found in medicines. Since many institutes around the world prefer to use open source software, G-SRS uses CDK in its default configuration.

The AMP-PD program, which is managed through FNIH, aims to identify and validate the most promising biological targets for therapeutics. AMP-PD has listed Alena Fedarovich and Leonya Ivanov from Rancho BioSciences on their websites showing how we/they utilized our Smart Converter tool - a set of Python and Java based custom scripts to perform data curation and update & format studies for loading into the AMP PD Knowledge Portal.

NIH’s Moonshot Project To Globally Register Medicinal Ingredients

January 31, 2020 | What’s in a name? When it comes to ingredients found in medicine, quite a lot of important detail. That’s why NIH’s NCATS (National Center for Advancing Translational Sciences) has been working to marshal a definitive resource for medicinal ingredients.

We would like to keep you updated with Rancho News that will include papers, posters, meetings we will be attending, fun events, new Ranchers and much more.


Rancho BioSciences is continuing to grow globally. At our headquarters in San Diego we ran out of room so we moved to a larger space with lots of windows, multiple conference rooms, a hang out area and kitchen. Our new address is:

Rancho BioSciences, LLC
16955 Via Del Campo, Suite 200
San Diego
CA 92127