Explore Rancho BioSciences Services

Rancho BioSciences provides data curation services for Pharmaceutical and Biotech companies, as well as for Academic institutions, Foundations and Government. The services include data cataloging, data harmonization, ontology services, data dictionaries, application of F.A.I.R. principles, data models, data mapping and others. Rancho works with internal and public life science data including clinical trial, genomic, variant, assay, chemistry, microbiome, flow cytometry and imaging data. Rancho BioSciences is platform-agnostic and has a lot of experience formatting data for many commercial, internal, and public (open-source) platforms. The Rancho BioSciences team has robust and reproducible automated and manual curation workflows, which include application of controlled vocabularies from scientific ontologies and dictionaries and data models, such as CDISC, MeSH, MedDRA and SNOMED.

Rancho BioSciences

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Our Bioinformatics team can help answer scientific questions by analyzing your complex data. Whether you need a short-term boost in data analysis resources, or engage a specialized team for a long-term project, Rancho can support your requirements with projects including:

Rancho BioSciences
  • Gene expression, proteomics, and metabolomics differential expression/abundance
  • DNA or histone binding site analysis (ChIP-seq)
  • Single cell analysis
  • Genetic variant detection (single nucleotide variants, insertions/deletions, copy number variants, genome structure variants)
  • Association of genetic variants or gene expression profiles with disease, drug response, or clinical outcome
  • Development of predictive models using machine learning or logistic regression
  • Pathway analysis and functional enrichment analysis
  • Phylogenetics and sequence analysis
  • Survival analysis of clinical trial data
  • Development of research software or databases for custom analysis

By processing and integrating disparate data types, we can generate a comprehensive biological picture of a disease. This further informs practical biotech and pharmaceutical research and development, including applications in:

  • Precision Medicine: Matching drug profiles and human genetic profiles, stratification of patient cohorts, biomarker identification
  • Drug discovery: Mechanism of action studies, accelerating discovery pipelines, by intelligently screening results, polypharmacology applications
  • Translational medicine: Drug repositioning for new indications, companion, diagnostics, enabling cross-discipline communication

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Rancho BioSciences

If you need to work with big data, create a robust pipeline, or integrate disparate data sets by combining with new technologies, Rancho data scientists can help. Before writing a single line of code, we will meet with you to understand the problem and design a fit-for-purpose solution that may involve custom, open source, and commercial components. From there, we will leverage team members with experience in analytical services, including automation, cloud services, interactive visualization dashboards, or stand-alone software tools. Afterwards, we share all the code, document the project, and present findings to stakeholders. We are also available to provide training on new tools or longer-term support projects.

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Knowledge Mining

Rancho BioSciences Ph.D. and M.D. scientists excel at knowledge mining that includes:

  • Searching for datasets with specific attributes
  • Target profile reports
  • Data mining in public databases: NCBI, ChEMBL, ClinicalTrials.gov and others
  • Building Natural Language Processing (NLP) pipelines and creating training datasets for NLP
  • Building disease, genetic variant, microbiome, and drug knowledge bases
  • Annotation of publications: interactions, assays, drug activity and toxicity, clinical trials, etc.
  • Literature search based on customer needs
  • Search of Principal Investigators and grants for a research area of interest

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How To Get Started

How to get started? Email Services @RanchoBioSciences.com or call (760) 717-7881 to schedule an on line meeting to discuss your project and get a quote.

  • Step1

    Schedule a meeting to discuss project details and requirements. Types of data, volume and formats.

  • Step 2

    Rancho provides an estimate of time, costs, deliverables and risks to be edited and finalized.

  • Step 3

    Paperwork is processed.

  • Step 4

    Kick off meeting.

  • Step 5

    Weekly update meetings and communications in between.

  • Step 6

    Wrap up meeting, data handed over with complete documentation.