About Rancho BioSciences

Rancho BioSciences is on a mission to save lives through Data.


Rancho BioSciences vision is to be the leading data services company in the world leveraging domain knowledge and expertise to solve complex problems.

Who are Ranchers?

We are a group of Amazing scientists that are passionate about saving lives through data. We are all driven, innovative, creative, work hard and smart to support our clients. We have diverse scientific backgrounds with experience across all areas of disease, worked with all kinds of data, instruments, and platforms. We have worked in Pharma, Biotech, software companies and academia. We have come together at Rancho to make a difference. We truly care.

Rancho Team

Founder and CEO
VP Science and Technology
Associate Director
Associate Director

Business Development

PhD - Business Development
PhD - Business Development

Business Model

Rancho BioSciences is a fee for service Data Curation Company
We are here to serve you and provide solutions to complicated problems.

We have a team of experienced PhD and MD scientists around the world that deliver high quality work on time and on budget. Our goal is to support the life science community by curating and organizing all kinds of life science data for analysis and providing knowledge mining services to be leveraged by our clients to further their research to answer important questions. We are all passionate about our work and the impact it will have for patients and their families.

FTE Model

Hourly rate: Access to large pool of scientist with diverse backgrounds. We invoice monthly only for hours used.

  • You pick and choose what kind of domain expertise is needed and we send resumes for you to choose from
  • For larger projects we assign a project manager and you can keep the scientists and developers you like on call for your future projects

Project-Based

  • We discuss the project with you and we estimate how long it will take, what kind of resources will be needed and send a proposal with pricing
  • Daily rate: We can also work on smaller projects using our daily rate

Publications and Posters

Prediction of standard cell types and functional markers from textual descriptions of flow cytometry gating definitions using machine learning.

Journal: Wiley Clinical Cytometry 2022

Measuring Disease Phenotype Reversal of HD Related Genomics Signatures in Response to Therapeutic and Genetic Perturbations Using Posterior Probabilities

Poster: CHDI HD Therapeutics Conference 2022

Effect of Small Molecule Splicing Modulators on proteome and transcriptome of HD stem cell derived neurons

Poster: CHDI HD Therapeutics Conference 2022

PerturbDB: A Database of Huntington's Disease Perturbation Studies https://www.hdinhd.org/

Poster: CHDI HD Therapeutics Conference 2022

HDinHD: A Data Portal for Huntington's Disease Research https://www.hdinhd.org/

Poster: CHDI HD Therapeutics Conference 2022

Stage-Specific Disease Genes in the Cortex and Striatum

Poster: CHDI HD Therapeutics Conference 2022

SEQUIN: rapid and reproducible analysis of RNA-seq data in R/Shiny

Journal: bioRxiv 2022 Preprint

Expression analysis of Huntington disease mouse models reveals robust striatum disease signatures.

Journal: bioRxiv.org Preprint 2022

NCATS Inxight Drugs: a comprehensive and curated portal for translational research

Journal: Nucleic Acids Research 2022

Assessing the use of telemetric devices in preclinical safety studies in non-human primates - data aggregation step

Journal: Bio-IT World Conference & Expo 2021

Towards a comprehensive view of diagnoses in UK Biobank by data curation and aggregation.

Journal: Bio-IT World Conference & Expo 2021

HDinHD: A Rich Data Portal for Huntington’s Disease Research

​Journal: Journal of Huntington’s Disease 2021

Quantitation of CD137 and Nectin-4 expression across multiple tumor types to support indication selection for BT7480, a Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™)

Poster: SITC Conference 2021

NCATS- Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis

Journal: BioRxiv 2021

Building towards a computational infrastructure to aid in the interpretation of Bicycle® toxin conjugate response profiles.

Poster: BioIT World 2021

Molecular-based enrichment strategy for Nectin-4 targeted Bicycle toxin conjugate BT8009

Poster: American Association for Cancer Research April 2021

Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical trials.

Journal: Data Intelligence 2021

Application of MCAT questions as a testing tool and evaluation metric for knowledge graph based reasoning systems.

Journal: Clinical and Translational Science 2021

HD Mouse Striatum RNA and Protein Disease Signatures

Poster : CHDI Annual Conference 2021

HD Phenocopy Disease Share Dysregulated Genes with HD
Poster : CHDI Annual Conference 2021

Searching for Genomic Biomarkers for Major
Depressive Disorder in Peripheral Immune Cells

Journal: Biological Psychiatry 2020

HTT protein nomenclature: The challenge with variable domains

Poster: CHDI Conference 2020

Global Substance Registration System: consistent scientific descriptions for substances related to health

Journal: Nucleic Acids Research 2020

An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD)

Journal: Journal of Biomedical Semantics 2020

Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease

Journal: Leukemia 2019

The NCATS BioPlanet - an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics

Journal: Frontiers in Pharmacology 2019

Aggregation and integration of UKbiobank phenotypes data for downstream analysis

Meeting: BioIT 2019

NCATS Stitcher: Data integration and guided Curation tool

Meeting: BioIT 2019

Data deluge: challenges and solutions in implementing a precision medicine approach to create the TRACK-TBI information Commons

Meeting: BioIT 2019

Major Depressive Disorder Is Associated With
Differential Expression of Innate Immune and
Neutrophil-Related Gene Networks in Peripheral
Blood: A Quantitative Review of Whole-Genome
Transcriptional Data From Case-Control Studies

Journal: Biological Psychiatry 2019

Expression concordance of 325 novel RNA biomarkers between data generated by NanoString nCounter and Affymetrix GeneChip

Journal: Disease Markers 2019

A predictor of pathological complete response to neoadjuvant chemotherapy stratifies triple negative breast cancer patients with high risk of recurrence

Journal: Scientific Reports 2019

A novel panel of 80 RNA biomarkers with differential expression in multiple human solid tumors against healthy blood samples

Journal: International Journal of Molecular Sciences 2019

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

Journal: Blood 2018

Aggregation and integration of UKbiobank phenotypes data for downstream analysis

Meeting: ASHG 2018

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

Journal: Leukemia 2018

Replicable and coupled changes in innate and adaptive immune gene expression into case-control studies of blood Microarrays in major depressive disorder

Journal: Biological Psychiatry 2017

Philanthropy

Rancho BioSciences' mission is to find cures to save lives. This is the passion in every single person working at Rancho and what motivates all of us to bring our A game every day. As a community we also give back to help those in need. Here are some of the organizations we are helping.

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