About Rancho BioSciences
Rancho BioSciences is on a mission to save lives through Data.
Rancho BioSciences vision is to be the leading data services company in the world leveraging domain knowledge and expertise to solve complex problems.
Who are Ranchers?
We are a group of Amazing scientists that are passionate about saving lives through data. We are all driven, innovative, creative, work hard and smart to support our clients. We have diverse scientific backgrounds with experience across all areas of disease, worked with all kinds of data, instruments, and platforms. We have worked in Pharma, Biotech, software companies and academia. We have come together at Rancho to make a difference. We truly care.
Rancho Team
Business Development
Publications and Posters
Prediction of standard cell types and functional markers from textual descriptions of flow cytometry gating definitions using machine learning.
Journal: Wiley Clinical Cytometry 2022
Measuring Disease Phenotype Reversal of HD Related Genomics Signatures in Response to Therapeutic and Genetic Perturbations Using Posterior Probabilities
Poster: CHDI HD Therapeutics Conference 2022
Effect of Small Molecule Splicing Modulators on proteome and transcriptome of HD stem cell derived neurons
Poster: CHDI HD Therapeutics Conference 2022
PerturbDB: A Database of Huntington's Disease Perturbation Studies https://www.hdinhd.org/
Poster: CHDI HD Therapeutics Conference 2022
HDinHD: A Data Portal for Huntington's Disease Research https://www.hdinhd.org/
Poster: CHDI HD Therapeutics Conference 2022
Stage-Specific Disease Genes in the Cortex and Striatum
Poster: CHDI HD Therapeutics Conference 2022
SEQUIN: rapid and reproducible analysis of RNA-seq data in R/Shiny
Journal: bioRxiv 2022 Preprint
Expression analysis of Huntington disease mouse models reveals robust striatum disease signatures.
Journal: bioRxiv.org Preprint 2022
NCATS Inxight Drugs: a comprehensive and curated portal for translational research
Journal: Nucleic Acids Research 2022
A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research
Journal: Journal of Chemical Information and Modeling 2022
Assessing the use of telemetric devices in preclinical safety studies in non-human primates - data aggregation step
Journal: Bio-IT World Conference & Expo 2021
Towards a comprehensive view of diagnoses in UK Biobank by data curation and aggregation.
Journal: Bio-IT World Conference & Expo 2021
HDinHD: A Rich Data Portal for Huntington’s Disease Research
Journal: Journal of Huntington’s Disease 2021
Quantitation of CD137 and Nectin-4 expression across multiple tumor types to support indication selection for BT7480, a Bicycle tumor-targeted immune cell agonist™ (Bicycle TICA™)
Poster: SITC Conference 2021
NCATS- Directed Differentiation of Human Pluripotent Stem Cells into Radial Glia and Astrocytes Bypasses Neurogenesis
Journal: BioRxiv 2021
Building towards a computational infrastructure to aid in the interpretation of Bicycle® toxin conjugate response profiles.
Poster: BioIT World 2021
Molecular-based enrichment strategy for Nectin-4 targeted Bicycle toxin conjugate BT8009
Poster: American Association for Cancer Research April 2021
Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical trials.
Journal: Data Intelligence 2021
Application of MCAT questions as a testing tool and evaluation metric for knowledge graph based reasoning systems.
Journal: Clinical and Translational Science 2021
HD Mouse Striatum RNA and Protein Disease Signatures
Poster : CHDI Annual Conference 2021
HD Phenocopy Disease Share Dysregulated Genes with HD
Poster : CHDI Annual Conference 2021
Searching for Genomic Biomarkers for Major
Depressive Disorder in Peripheral Immune Cells
Journal: Biological Psychiatry 2020
HTT protein nomenclature: The challenge with variable domains
Poster: CHDI Conference 2020
Global Substance Registration System: consistent scientific descriptions for substances related to health
Journal: Nucleic Acids Research 2020
An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD)
Journal: Journal of Biomedical Semantics 2020
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease
Journal: Leukemia 2019
The NCATS BioPlanet - an integrated platform for exploring the universe of cellular signaling pathways for toxicology, systems biology, and chemical genomics
Journal: Frontiers in Pharmacology 2019
Aggregation and integration of UKbiobank phenotypes data for downstream analysis
Meeting: BioIT 2019
NCATS Stitcher: Data integration and guided Curation tool
Meeting: BioIT 2019
Data deluge: challenges and solutions in implementing a precision medicine approach to create the TRACK-TBI information Commons
Meeting: BioIT 2019
Major Depressive Disorder Is Associated With
Differential Expression of Innate Immune and
Neutrophil-Related Gene Networks in Peripheral
Blood: A Quantitative Review of Whole-Genome
Transcriptional Data From Case-Control Studies
Journal: Biological Psychiatry 2019
Expression concordance of 325 novel RNA biomarkers between data generated by NanoString nCounter and Affymetrix GeneChip
Journal: Disease Markers 2019
A predictor of pathological complete response to neoadjuvant chemotherapy stratifies triple negative breast cancer patients with high risk of recurrence
Journal: Scientific Reports 2019
A novel panel of 80 RNA biomarkers with differential expression in multiple human solid tumors against healthy blood samples
Journal: International Journal of Molecular Sciences 2019
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Journal: Blood 2018
Aggregation and integration of UKbiobank phenotypes data for downstream analysis
Meeting: ASHG 2018
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Journal: Leukemia 2018
Replicable and coupled changes in innate and adaptive immune gene expression into case-control studies of blood Microarrays in major depressive disorder
Journal: Biological Psychiatry 2017
Philanthropy
Rancho BioSciences' mission is to find cures to save lives. This is the passion in every single person working at Rancho and what motivates all of us to bring our A game every day. As a community we also give back to help those in need. Here are some of the organizations we are helping.
